The term "down-in-mouth" is an expression used to describe someone who appears sad, low-spirited, and disheartened. Some antonyms for "down-in-mouth" include happy, cheerful, delighted, pleased, joyful, elated, and ecstatic. These words describe a person's well-being as positive, optimistic, and hopeful. When someone is not "down-in-mouth," they are more likely to be energetic, proactive, and creative. People who are not "down-in-mouth" tend to have better relationships, better health, and a more fulfilling life. By cultivating a positive mindset, individuals can overcome feelings of discouragement, depression, and despair, and maintain a more balanced emotional state.