Guilt-free is a term that implies ease of mind without the weight of wrongdoing or negative consequences. Some antonyms for guilt-free include regretful, remorseful, guilty, and culpable. These terms convey a sense of self-reproach and moral responsibility for one's actions. They denote a lack of innocence and a sense of wrongdoing or error in judgment. Alternately, indifferent, unapologetic, and carefree are also antonyms to guilt-free, conveying a sense of detachment or unconcerned attitude towards one's actions or their consequences. The choice of antonym for guilt-free may depend on the context, tone, and intended emotional response.