"Clean-handed" is an adjective used to describe someone who is innocent, blameless or free from guilt. The antonyms of this term are those that portray the opposite meaning. Some of the commonly used antonyms of "clean-handed" include; guilty, blameworthy, responsible, accountable and culpable. These words are often used when describing individuals who have committed an offense, wrongly accused or involved in a wrongdoing. It is important to note that while "clean-handed" refers to someone who did not commit a crime, being guilty of an offense doesn't necessarily mean that the individual is entirely evil or unworthy of forgiveness.