The phrase "hot up" is an informal expression that means to become more intense, exciting, or active. There are several antonyms for this phrase, including "cool down," which means to become calmer or less intense. Another antonym is "slow down," which means to decrease in speed or activity. "Calm down" is another opposite of "hot up," which means to become less agitated or stressed. Additionally, "quiet down" can be an antonym for this phrase, meaning to become less noisy or disruptive. Overall, these antonyms provide a range of options to express the opposite of "hot up" in various contexts.