Antonyms for the word "pep up" could be "calm down," "relax," or "soothe." These terms describe the opposite effect of "pep up," which is to invigorate, energize, or stimulate. Other potential antonyms for "pep up" might include "depress," "demotivate," or "discourage." These terms convey a more negative influence on a person's energy and motivation levels, as opposed to the positive impact of "pep up." Depending on the context and connotations of a particular phrase, there may be different antonyms that are most appropriate. Nonetheless, in general, words like calm, relax, and soothe provide a contrast to the idea of pepping up or energizing.