Instantiate is a verb that refers to the act of creating an instance of an object or a process. Its antonyms are words that describe the opposite action, such as destroy or remove. For instance, the word "invalidate" means to nullify or cancel something that was previously established, thus making the instantiation of a process or object impossible. "Abolish" and "dismantle" are other antonyms that suggest the elimination of an instance or process. Conversely, "preserve" and "maintain" are words that indicate the continuity of an instantiation or a process, implying that it remains unaffected by external factors. Overall, the antonyms of "instantiate" describe the opposite side of the coin, highlighting the importance of maintaining, preserving, or dismantling an instance of an object or process, as necessary.