The word "intermediated" is used to describe an action that involves a mediator or someone acting as a middleman between two parties. The antonyms for this word are often related to direct communication or action, without the presence of a middleman. For example, "directed" or "guided" imply that there is no need for an intermediary, whereas "mediation-free" suggests that there is no middle person involved in the process. Other antonyms could be "unassisted," "self-directed," or "unaided," all of which indicate that no external help or negotiation is required. Ultimately, the choice of antonym for "intermediated" will depend on the context and the specific meaning that the speaker wishes to convey.