Kupffer's cells are a type of specialized cell found in the liver. They are also referred to as stellate macrophages, hepatic macrophages, or sinusoidal lining cells. They are responsible for removing bacteria and foreign particles from the bloodstream that flows through the liver. Kupffer's cells play a critical role in liver function and are essential for maintaining overall health. Typical synonyms for Kupffer's cell include periportal macrophage, reticuloendothelial cell, sinusoidal macrophage, and endothelial macrophage. Regardless of the name used, these cells are vital for the liver's proper functioning and maintaining a healthy body. Therefore, any issues concerning the cells must be handled with utmost urgency.