The antonyms of "make run at" are quite a few, as the phrase suggests an aggressive approach towards someone or something. Antonyms for "make run at" could be peace, harmony, and calmness. Other antonyms that would fit could include retreat, withdraw, and concede. If someone wants to make peace with someone else, then they would not "make a run at" them. As such, it's essential to understand the context in which the term is used, so one can determine the most suitable antonym to use in its place. Antonyms for "make a run at" represent a desire for a more peaceful, less confrontational approach.