The antonyms for the phrase "most cast-down" includes words like hopeful, optimistic, confident, encouraged, proud, exultant, elated, content, and uplifted. These words express positive emotions, contrasting the feeling of being dejected or discouraged. Hopeful means having a positive outlook towards the future or a particular situation. Optimistic means expecting positive outcomes or believing good things will happen. Confident means having trust in oneself or one's abilities. Encouraged means to feel supported or motivated. Overall, these words offer a sense of positivity, hope, and confidence, which are the opposite of feeling cast-down or disheartened.