The antonyms for the word "most depressive" can be "most joyful," "most cheerful," "most optimistic," "most happy" and "most lively." These are the words that carry the exact opposite meaning of the word "depressive." Instead of feeling low-spirited, these words bring up a sense of positivity and happiness. When someone is feeling most joyful, they are experiencing an intense feeling of happiness that can lift their spirits and make them feel good. Similarly, being most cheerful is a state of mind that is lively, festive, and full of fun. Being most optimistic enables people to approach life with a positive attitude and most lively makes you energetic and full of life.