Antonyms for the word 'most disheartened' are words that express feelings of hopefulness, encouragement or optimism. The antonyms could be, 'encouraged', 'hopeful', 'confident', or 'optimistic'. When someone is disheartened, it means they have lost all hope or confidence in a situation, so providing encouragement and offering words of optimism can help them regain their composure. People who are encouraged or optimistic tend to have a positive mindset which helps in building a better future. Therefore, it is essential to choose our words carefully when trying to motivate or encourage someone who may be feeling most disheartened.