Most good-for-nothing is a phrase used to describe someone or something that is useless, worthless, or has no value. The antonyms for this phrase, therefore, would be words that express the opposite meaning. Such antonyms could include, valuable, useful, competent, skilled, productive, reliable, and effective. These words are used to describe individuals or things that possess worth, ability, and usefulness. An example of the use of antonyms for most good-for-nothing could be in the context of an employee's evaluation. Instead of being labeled as most good-for-nothing, an employee could be described using the antonyms, such as reliable, efficient, and skilled.