The antonyms for the phrase "most piqued" can vary depending on the context of its usage. However, some common antonyms for piqued include calm, pleased, uninterested, disinterested, and indifferent. When one is not emotionally aroused, their interest level decreases or remains constant, making them uninterested. Conversely, when individuals are pleased, they are happy and satisfied, and their emotional state is positive. Disinterested or indifferent, on the other hand, means that someone has little or no interest in something. Thus, depending on the context where "most piqued" is used, its antonyms can vary and include other words that describe different levels of emotional arousal or indifference.