The antonyms for the word "most streetwise" can be naive, gullible, unsophisticated, innocent, and inexperienced. While streetwise refers to the understanding and awareness gained through life experiences in urban environments, the antonyms suggest an individual lacking in such exposures. A person who is naive and gullible usually falls prey to scams and frauds due to their lack of practical knowledge. An unsophisticated or innocent person may not even identify or comprehend the dangers of the streets. An inexperienced individual may find themselves lost or unsure of how to navigate through unfamiliar areas, making them vulnerable to exploitation.