The word "most unburdened" means feeling free and relieved. To find antonyms for this word, one needs to look for words that indicate being burdened or weighed down. Some antonyms for "most unburdened" could include "burdened," "loaded," "weighed down," "heavyhearted," "oppressed," or "troubled." These words suggest a feeling of heaviness or being weighed down by responsibilities, stress, or worries. Antonyms for "most unburdened" depict a state of mind that is opposite, indicating that one is feeling weighed down or burdened in some way.