The phrase "nickel-and-dime" is often used to describe small or insignificant things. Antonyms for this phrase could include "major," "significant," or "important." These antonyms suggest that something is substantial or critical, rather than trivial. Other antonyms might include "expensive," "luxurious," or "extravagant," which connote financial wealth rather than penny-pinching. In contrast, "frugal," "economical," or "budget-friendly" might suggest responsible and thoughtful spending. Whatever the antonym, the implication is that something is valuable or noteworthy, rather than inconsequential or insignificant.