Penny ante refers to a small amount of money or something that is insignificant or trivial. The antonyms for penny ante are significant, substantial, and notable. Significant means important or meaningful, whereas substantial means substantial or considerable. Notable refers to something that is noteworthy or remarkable. These antonyms represent the opposite of penny ante, indicating something with value, importance, or a high degree of quality. Penny ante can also mean something lowly or unimportant, so antonyms such as distinguished, notable, and prominent are also suitable. Overall, antonyms for penny ante illustrate an opposite perspective, emphasizing importance or value.