Pancreatic fibrosis is a medical condition that affects the pancreas and causes the development of fibrous tissue, which can lead to the loss of function of this vital organ. This disease can also be referred to as pancreatic sclerosis, pancreatic fibrotic disease, or pancreatic fibroplasia. Other synonyms include chronic pancreatitis, pancreatic inflammation, and pancreatic damage. The symptoms associated with pancreatic fibrosis may include abdominal pain, jaundice, nausea, and weight loss. Treatment options for this condition may include pain management, lifestyle changes, and/or surgery. An early diagnosis can help to prevent further progression and complications of pancreatic fibrosis.