The word "seem" can be replaced by a number of synonyms depending on the intended meaning and context of the sentence. Some common synonyms for "seem" include "appear," "look," "give the impression," "give the appearance," "suggest," "imply," "indicate," "betoken," "convey," and "portray." These synonyms can help to add variety and depth to writing, allowing for more nuanced descriptions of the way things appear or are perceived. Additionally, the use of synonyms can help to avoid repetitive language and make writing more interesting to read.