Semi-synthetic gene construction involves creating DNA molecules by combining natural DNA sequences with synthesized ones. Synonyms for this term could include "partially artificial gene assembly," "hybrid genetic engineering," or "semi-artificial gene synthesis." Alternatively, one could refer to this process as "chimeric gene construction," which emphasizes the hybrid nature of the resulting DNA molecule. It may also be called "semi-biological gene design" or "semi-organic gene creation" to highlight the combination of natural and synthetic components. Other possible synonyms might include "semi-synthetic gene synthesis" or "partially-manufactured gene development." Regardless of the terminology used, this process allows researchers to design and construct complex genetic circuits with a greater degree of precision and flexibility than conventional genetic engineering techniques.