The antonyms for substance abuser are numerous, and they all refer to someone who does not engage in harmful and destructive behaviors related to drugs, alcohol, and other substances. These individuals can be described as sober, clean, drug-free, abstinent, non-addicted, and healthy. They may also be referred to as responsible, disciplined, focused, and goal-oriented, as they prioritize their well-being and avoid activities and substances that could compromise their health and future. By practicing self-care and making positive choices, these individuals lead productive, fulfilling lives, and serve as role models for others who struggle with substance abuse issues.