The phrase "takes five" originally means to take a five-minute break, usually used in performing arts like theatre or music. Some synonyms for this phrase include "take a breather," "take a rest," "take a pause," "take a break," or "take a moment." These synonyms could be used interchangeably depending on the situation. You may use them in the workplace, during a workout, or even during a conversation. These phrases typically mean taking a short break to refresh the mind or relax the body before resuming work again. They could also imply taking a break to ponder and reflect on certain things.