Werdnig-Hoffman disease, also known as spinal muscular atrophy type 1 (SMA1), is a rare genetic disorder that affects the muscles used for movement. There are several synonyms for this disease, including infantile spinal muscular atrophy, acute Werdnig-Hoffman disease, and infantile progressive muscular atrophy. Regardless of what it is called, the symptoms of this disease are similar, including muscle weakness and poor muscle tone. Unfortunately, there is currently no cure for Werdnig-Hoffman disease, but there are treatment options available that can help manage symptoms and improve quality of life. With early diagnosis and treatment, it is possible for those with this condition to live longer and more fulfilling lives.