Antonyms for the word "amuses with" include boring, disappointing, irritating, discouraging, and distressing. These terms indicate the opposite effect of amusement, meaning that they cause dissatisfaction, apathy, anger, or sadness. When someone is not amused with something, they may feel like it is a waste of time or even offensive. Therefore, it is important to consider the audience's preferences and interests when trying to amuse them. Sometimes, humor or entertainment can backfire and have the opposite effect, making people feel uncomfortable, embarrassed, or offended. To avoid this, it is better to be aware of the context and choose the right kind of amusement that fits the occasion and the audience.