The term "doped out" typically means to be under the influence of drugs or alcohol, and it's considered a negative term. Some antonyms for "doped out" could include sober, alert, clear-headed, focused, attentive, and mindful. These words imply a state of being present and aware, without the numbness or distortion that drugs or alcohol can cause. Another antonym for "doped out" could be energized, motivated, or inspired, which suggests a positive and productive mindset. Choosing an antonym that reflects a healthy and intentional way of living can help create a positive mindset and foster a successful lifestyle.