Maculation refers to the act of making or becoming marked with spots or blotches. For this word, suitable antonyms would include words like pure, spotless, clean, or clear. Pure means free of any contamination, blemish or impurity. Spotless refers to something that is entirely free of spots, stains or blemishes. Clean means free of dirt or impurities. Clear signifies something that is free from any cloudiness, obscurity, or uncertainty. These antonyms are helpful in describing something that is unblemished, untainted, pristine or transparent. By considering these antonyms, we can get a better understanding of what maculation means and how it relates to other words in the English language.