The word 'most tuneless' can be used to describe something that lacks melody or musicality. However, there are several antonyms for this term that describe music or sounds that are harmonious, melodious, rhythmic, and tuneful. Some examples of antonyms for 'most tuneless' include melodious, sonorous, harmonious, euphonious, symphonic, and rhythmic. These terms suggest music or sounds that are pleasing to the ear, well-balanced, and rhythmic. Whether it's a soothing melody or a rhythmic beat, these antonyms for 'most tuneless' describe music that captures the mood and emotions of the listener, inspiring feelings of joy and positivity.