Obsecrated is a term that is rarely used in conversations and writing, and it is rare to find its antonyms listed in the dictionary. However, based on its definition, which means "to invoke, appeal to, or implore by solemn affirmation," some possible antonyms include disrespect, irreverence, neglect, disregard, and blasphemy. These words emphasize the opposite of obsecration, indicating a lack of reverence, honor, or appeal. In contrast to obsecrated, these antonyms suggest profanity or sacrilege instead of holiness or sacredness. While they may not perfectly capture the opposite of obsecrated, these antonyms can help convey the ideas of disrespecting or ignoring the divine.