The opposite of "over-joyed" can be defined as feeling unhappy or sad. Some possible antonyms of "over-joyed" are disheartened, discouraged, dispirited, downhearted, melancholic, sorrowful, unhappy, miserable, dejected, crestfallen, or glum. These words suggest that someone is experiencing a lack of pleasure, enthusiasm, or contentment, and may feel disappointed, disillusioned, or drained. Alternatively, some other antonyms of "over-joyed" may be neutral or moderate emotions such as calm, indifferent, composed, serene, peaceful, placid, or resigned. These words imply that someone is not excessively excited or exuberant, but rather maintains a balanced, steady, or peaceful state of mind.