The word "pre-determining" can be defined as setting a decision or outcome beforehand. Antonyms for pre-determining include uncertain, undecided, and unpredictable. When something is uncertain, it means that the outcome is unknown, and there is a wide range of possibilities. Undecided means that a decision has not yet been made and that there are options to choose from. Predictable refers to something that can be anticipated based on prior experience or knowledge. An antonym for pre-determining allows for more flexibility and openness, which can be beneficial in various contexts, such as business, relationships, or creative pursuits.