The word "pre-dispose" means to make someone more likely to do or experience something. Some antonyms for "pre-dispose" include discourage, dissuade, disincline, and deter. To discourage someone is to actively prevent them from doing something. When you dissuade someone, you persuade them not to do something. Disinclination means a lack of enthusiasm or willingness to do something. Thus, if you disincline someone, you make them less interested in something. Lastly, if you deter someone, you dissuade them from doing something by instilling fear or doubt in them. All these antonyms play a significant role in restraining or decreasing the likelihood of an event or action.