Run-down is an adjective that describes something in a poor state of repair or condition. Some synonyms for run-down include dilapidated, decrepit, shabby, rundown, tumbledown, and worn-out. These words describe something that is old, neglected, and often in need of repair or replacement. Other synonyms include disheveled, threadbare, seedy, rundown, and run-down. These words describe something that is unkempt or untidy, often due to neglect or lack of maintenance. Whether it's an old building or a person who looks tired and worn out, these words capture the sense of wear and tear that comes with neglect and disrepair.