Tangier Disease Neuropathy, formally known as familial HDL deficiency or Tangier disease, is a rare genetic disorder characterized by abnormal levels of high-density lipoprotein (HDL) cholesterol in the body. This condition can lead to progressive neuropathy, a dysfunction of the peripheral nerves that affects movement and sensation. While "Tangier Disease Neuropathy" is the specific term used to describe this condition, other synonyms can also be employed to refer to this disorder. Some alternative names for Tangier Disease Neuropathy include Familial HDL deficiency, Analphalipoproteinemia, HDL deficiency, and Tangier disease. These interchangeable terms are used in medical literature and discussions to identify and categorize this neurological condition.