The term "up-town" typically refers to a fashionable or affluent area of a city. Antonyms for "up-town" would include "down-town," which refers to the central, commercial district of a city, often less affluent and less fashionable. "Rural" might also be considered an antonym, since it refers to areas that are outside of cities and generally characterized by lower population density and less urban amenities. "Suburban" is another antonym, which refers to residential areas located outside of big cities but offering more amenities than rural areas. Finally, "working-class" or "low-income" might also be considered antonyms, as they represent areas that are generally less affluent or fashionable than an up-town area.