When something wears off, it means it diminishes or fades away gradually, often referring to the effect of a substance on the body. There are various synonyms that can be used instead of 'wear off,' such as fade, dissipate, diminish, ebb, recede, wane, abate, subside, and lessen. For example, the effects of caffeine gradually dissipate over time, and the high from marijuana eventually fades. Similarly, feelings of anxiety or stress may ebb away with meditation or a relaxing activity. People may hope that their headache will subside or lessen after taking medication. When we use alternative synonyms for 'wear off,' it adds variety and nuance to our language.