The phrase "what's upped" is a colloquial term used to ask someone how they are doing or what is happening in their lives. There are many synonyms for this phrase, including "how are you?", "what's going on?", "what's new?", and "what's happening?". These phrases are commonly used in casual conversations and can help break the ice when meeting someone new. Other variations of this phrase include "how's it going?", "what's the word?", and "what's the buzz?". Whichever phrase you choose, it's a great way to start a conversation and show that you care about the other person's well-being.