"What's upping" is slang for "what's going on" or "what's happening." There are a variety of synonyms for this phrase that can be used depending on the situation and tone of the conversation. Some alternatives include "what's new," "how's it hanging," "what's the scoop," "what's the word," "how are things," "what's shaking," "what's cooking," and "what's the buzz." These phrases are all used to inquire about someone's current situation, mood, or events in their life. Each phrase offers a slightly different tone and connotation, so it is important to choose one that is appropriate for the conversation.