The term "cleans up on" is often used to describe someone who has great success or wins big in a particular situation. However, there are many antonyms that can be used to convey the opposite meaning of this phrase. For example, "loses big" is an antonym that describes an individual who experiences a significant loss or failure in a particular situation. "Struggles" and "flounders" are additional antonyms that can be used to convey an individual's difficulty in achieving success. Conversely, "settles" and "does alright" are antonyms that convey moderate success or an outcome that is satisfactory, but not exceptional.