Prostration refers to the state of complete physical or mental exhaustion, weakness or helplessness. Some of the synonyms for it include collapse, exhaustion, fatigue, debilitation, lassitude, weakness, lethargy, frailty, feebleness, powerlessness, and enervation. These words all relate to the feeling of extreme tiredness or weakness, and can be used interchangeably with prostration in certain contexts. For example, a person who has been working non-stop for hours might experience symptoms of prostration, such as exhaustion and weakness. In this case, synonyms like fatigue or collapse could also be used to convey the same idea. The choice of word will depend on the context and the writer's preferred style.