Big break is a common phrase that refers to an opportunity, opening, or chance that could significantly improve one's career, life, or situation. However, there are many other synonyms for the famous term. For example, breakthrough, turning point, golden opportunity, stroke of luck, game-changer, pivotal moment, life-changer, and fortune-changing moment. These synonyms signify a significant change or advancement that can lead to long-lasting benefits or success. For that reason, using these phrases can make your writing more descriptive and engaging while avoiding repetition. Remember, these expressions refer to a rare or unique circumstance that could shape one's future, so choose wisely!