The antonyms for the familiar tune are various, and they convey different sentiments depending on the context. A strange melody can be an antonym for a familiar tune, which could evoke feelings of intrigue or unease. An unknown melody could also be an antonym, bringing an aura of ambiguity and mystery. A forgettable melody is the antithesis highlighting the importance and staying-power of a familiar tune. A confusing, unstructured or disjointed melody represents an antonym to a familiar tune with its structured and recognizable rhythm. A challenging or complex melody could also be an opposing force to a familiar tune with a simple, easy-to-follow melody.