High spirits are often used to describe feelings of happiness, joy, and enthusiasm. However, there are several antonyms for "high spirits" that represent the opposite emotions. Low spirits, for example, describe a feeling of sadness, dejection, and discouragement. Other antonyms for high spirits include depression, despair, misery, and gloom. People experiencing low spirits may feel disheartened, lonely, or uninterested in life. It's important to recognize when negative emotions start to affect your behavior and seek help if needed. While feeling low spirits is a natural part of the human experience, it's important to take steps to proactively combat these feelings and work back towards high spirits.