Bust Up is a phrasal verb that means to end or destroy a relationship, friendship, or partnership. There are several synonyms that can be used instead of the phrase - Bust up. One of them is "break up". It is a common term used in the context of ending a romantic relationship. "Split up" is another synonym that can be used in the same context. However, it can be used to indicate the end of any relationship. "Disintegrate" is a synonym that can be used to describe the end of a group or an organization. Other synonyms include "separate", "fall apart", "dissolve", "dismantle" and "disband".