The antonyms for "calling up on" are "ignoring," "avoiding," and "neglecting." When we call up on someone, we are seeking their assistance, advice, or presence. However, ignoring someone means we are intentionally not acknowledging them or their needs. Avoiding someone means we do not want to engage with them, either because of a conflict or simply feeling uncomfortable. Neglecting someone means we fail to fulfill our responsibilities towards them, such as failing to check up on a friend who is going through a tough time. When we choose to ignore, avoid or neglect someone, we miss out on opportunities to build meaningful relationships and offer support to others.