Bring to naught can also be expressed as nullify, cancel, abolish, invalidate, thwart, annihilate, eliminate, negate, quash, and frustrate. Each of these words has a slightly different connotation, but they all convey the meaning of making something ineffective or zeroing out its impact. One might nullify a contract, cancel a reservation, or frustrate an opponent's strategy. Annihilate suggests a more complete destruction, while negate implies negating the effects of something without necessarily destroying it. Quash might suggest an effort to suppress or silence something, while eliminate more commonly refers to removing or exterminating something. Ultimately, each synonym offers a unique nuance to the meaning of bring to naught.