De vitalize refers to a state of being weakened or stripped of vitality. Antonyms for this word include vivify, energize, invigorate, stimulate, enliven, rejuvenate, refresh, revitalize, reanimate, animate, and revive. These words refer to a state of being filled with energy, positivity, and enthusiasm. They represent a state where something is thriving, active, and alive. To vivify something implies adding vitality, while to energize means to fill with energy. To invigorate something implies making it stronger and to stimulate means to activate. Rejuvenate and refresh both refer to a state of being renewed, while regenerate implies rebuilding something. Ultimately, the antonyms for de vitalize signify restoration to life and energy.