De-file means to spoil or damage the purity, integrity or original condition of something. Its antonyms include words such as purify, cleanse, sanitize or clean. These terms signify the actions of removing dirt, germs, or unwanted elements from a surface, object, or concept. Purify implies the elimination of impurities, sanitize is the reduction of the amount of germs, cleanse is the removal of dirt, and clean refers to the overall state of being free from impurities. These antonyms represent the opposite of de-file, which denotes the defiling or dirtying of something that was previously clean and pure.